A. 英語論文・総説 (Publication Lists)

※ 胚子・胎児関連英語論文（査読あり）のうち本研究室が主体の研究には1,2,3 …が、共同研究者が主体の研究には①②③ …が振られています

2025年

70. Ishida N, Ueda Y, Kanahashi T, Matsubayashi J, Imai H, Yamada S, Takakuwa T.Hierarchical loop formation in human midgut during physiological umbilical herniation, J Anatomy 2024, in press

2024年

69. Iwasa Y, Kanahashi T, Imai H, Otani H, Yamada S, Takakuwa T. Human trapezius muscle development during early fetal period. J Anatomy 2024, 245, 663-673, doi: 10.1111/joa.14116, (表紙に採用されました）https://doi.org/10.1111/joa.14082

68. Isotani N, Kanahashi T, Imai H, Yoneyama A, Yamada S, Takakuwa T. Regional differences in the umbilical vein and ductus venosus at different stages of normal human development. Anat Rec (Hoboken), 2024, 307, 3306-3326.DOI:10.1002/ar.25421

67. Iwasa Y, Kanahashi T, Imai H, Otani H, Yamada S, Takakuwa T. Formation of tendinous intersections in the human fetal rectus abdominis, J Anatomy 245,365-376, 2024, DOI: 10.1111/joa.14064

66. Kanahashi T, Matsubayashi J, Imai H, Yamada S, Otani H, Takakuwa T. Sexual dimorphism of the human fetal pelvis exists at the onset of primary ossification, Communications Biology, 2024, 7:538, https://doi.org/10.1038/s42003-024-06156-y

65. Saizonou MA, Kitazawa H, Kanahashi T, Yamada S, Takakuwa T, Epithelial development of the urinary collecting system in the human embryo, PLOS ONE 19(4): e0301778.　https://doi.org/10.1371/journal.pone.0301778

64. Ishiyama-Takara H, Matsubayashi J, Yamada S, Takakuwa T, Height difference between the right and left metanephroi during early human fetal development, Congenit Anom 64(3) 164-166, 2024 doi.org/10.1111/cga.12565

63. Iwasa Y, Kanahashi T, Imai H, Otani H, Yamada S, Takakuwa T, Pyramidalis muscle formation during human embryonic and early fetal periods, Congenit Anom 2024, 64, 32-39, DOI: 10.1111/cga.12551

表紙に採用されました。https://doi.org/10.1111/cga.12522

62. Fujii S, Muranaka T, Matsubayashi J, Yamada S, Yoneyama A, Takakuwa T. Bronchial tree of the human embryo: Examination based on a mammalian model. J Anatomy 2024, 244(1), 159-169. http://doi.org/10.1111/joa.13946 .

61. Fukui N, Kanahashi T, Matsubayashi J, Imai H, Yoneyama A, Otani H, Yamada S, Takakuwa T. Morphogenesis of the pulmonary vein and left atrial appendage in human embryos and early fetuses. J Anatomy 2024(1), 142-155, https://doi.org/10.1111/joa.13941

○17　Ishida K, Ishikawa A, Yamada S, Takakuwa T, Aoyama T, Three-dimensional imaging analysis of the developmental process of posterior meniscofemoral ligaments in rat embryos. Cells Tissues Organs 2024, 213(5):357-367, DOI: 10.1159/000536108

査読なし

■ 八田桃佳　拡散テンソル画像を用いた水晶体線維細胞の配向性の検討, 臨床検査学教育, in press

■ 近嵐 尚、高桑 徹也、山田 重人、清水 昭伸 、ヒト胚子の脳の複数領域を対象とした条件付き統計的形状モデル 信学技報 

2023年

60. Takakuwa T, Saizonou MA, Fujii S, Kumano Y, Ishikawa A, Aoyama T, Imai H, Yamada S, Kanahashi T. Femoral posture during embryonic and early fetal development: An analysis using landmarks on the cartilaginous skeletons of ex vivo human specimens. PLoS One, 2023, 18(5): e0285190. https://doi.org/10.1371/journal.pone.0285190

59. Matsunari C, Kanahashi T, Otani H, Imai H, Yamada S, Okada T, Takakuwa T. Tentorium cerebelli formation during human embryonic and early fetal development. Anat Rec (Hoboken) 2023, 306(3), 515-526, DOI:10.1002/ar.25110

58. Kanahashi T, Imai H, Otani H, Yamada S, Yoneyama A, Takakuwa T. Three-dimensional morphogenesis of the human diaphragm during the late embryonic and early fetal period: Analysis using T1-weighted and diffusion tensor imaging. J Anat. 2023, 252(2),174-190, DOI: 10.1111/joa.13760
表紙に採用されました

⑯ Yoneyama A, Takamatsu D, Lwin TT, Yamada S, Takakuwa T, Hyodo K, Hirano K, Takeya S. Crystal-based X-ray interferometry and its application to phase- 2. Appl. Sci. 2023, 13, x. https://doi.org/10.3390/app13095424

査読なし

■ ten Donkelaar HJ, Yamada S, Shiota K, van der Vliet T, Vasung L, Takakuwa T. Chapter 1 (Overview of the Development of the Human Brain and Spinal Cord) in Clinical Neuroembryology (2023, Springer, Heidelberg)

2022年

57.  Nohara A, Owaki N, Matsubayashi J, Katsube M, Imai H, Yoneyama A, Yamada S, Kanahashi T, Takakuwa T. Morphometric analysis of secondary palate development in human embryos. J Anat, 2022, 241(6), 1287-1302, 2022, DOI:10.1111/joa.13745

56. Kakeya M, Matsubayashi J, Kanahashi T, Männer J, Yamada S, Takakuwa T. The return process of physiological umbilical herniation in human fetuses: the possible role of the vascular tree and umbilical ring. J Anat 2022, 241(3), 846-859. https://doi.org/10.1111/joa.13720

55. Kumano Y, Tanaka S, Sakamoto R, Kanahashi T, Imai H, Yoneyama A, Yamada S, Takakuwa T. Upper arm posture during human embryonic and fetal development. Anat Rec (Hoboken) 2022, 305 1682-1691, https://doi.org/10.1002/ar.24796

54. Yamazaki Y, Kanahashi T, Yamada S, Männer J, Takakuwa T. Three-dimensional analysis of human laryngeal and tracheobronchial cartilages during the late embryonic and early fetal period. Cells Tissues Organs, 2022, 211,1-15, https://doi.org/10.1159/000519160

⑮ Nakano S, Kodama R, Yamaguchi Y, Takakuwa T, Yamada S. 14_MCA-based Embryology and Embryo Imaging. Multidisciplinary Computational Anatomy-Principles and Clinical Application of MCA-based Medicine. Editor: Makoto Hashizume. Springer Japan, Tokyo, pp 121-130. https://doi.org/10.1007/978-981-16-4325-5_14

53. Takakuwa T. 13_Analysis of skeletal system during human early-fetal period based on MCA. Multidisciplinary Computational Anatomy-Principles and Clinical Application of MCA-based Medicine. Editor: Makoto Hashizume. Springer Japan, Tokyo, pp 103-119. https://doi.org/10.1007/978-981-16-4325-5_13

52. Takakuwa T. Three-dimensional analysis at human organogenesis. 12_Multidisciplinary Computational Anatomy-Principles and Clinical Application of MCA-based Medicine. Editor: Makoto Hashizume. Springer Japan, Tokyo, pp 107-112. https://doi.org/10.1007/978-981-16-4325-5_12

2021年

51. Terashima, M., Ishikawa A., Männer J., Yamada S.&Takakuwa T. (2021) Early development of the cortical layers in the human brain. J Anat, 239, 1039–1049. https://doi.org/10.1111/joa.13488

⑭ Katsube M, Yamada S, Takahashi N, Yamaguchi Y, Takakuwa, T, Yamamoto A, Imai H, Saito A, Vora S, Morimoto N, A 3D Analysis of Growth Trajectory and Integration During Early Human Prenatal Facial Growth, Scientific Rep 2021,  11:6867 https://doi.org/10.1038/s41598-021-85543-5

50. Takakuwa T, Shiraishi N, Terashima M, Yamanaka M, Okamoto I, Imai H, Ishizu K, Yamada S, Ishikawa A, Kanahashi T. Morphology and morphometry of the human early fetal brain: A three-dimensional analysis. J Anat; 239 (2) 498-516, 2021, https://doi.org/10.1111/joa.13433

■ Kanahashi T, Matsumura Y, Yamamoto M, Tanaka M, Nagao M. Comparison of the Xpert Carba-R and NG-Test CARBA5 for the detection of carbapenemases in an IMP-type carbapenemase endemic region in Japan. J Infect Chemother 2021; 27, 503-506. DOI:https://doi.org/10.1016/j.jiac.2020.11.001

49. Kitazawa H, Fujii S, Ishiyama H, Matsubayashi J, Ishikawa A, Yamada S, Takakuwa T. Nascent nephrons during human embryonic development: Spatial distribution and relationship with urinary collecting system. J Anat 2021; 238, 455-466, DOI: 10.1111/JOA.13308

48. Fujii S, Muranaka T, Matsubayashi J, Yamada S, Yoneyama A, Takakuwa T. Bronchial tree of the human embryo: categorization of the branching mode as monopodial and dipodial, PLoS One 16; e0245558, 2021, https://doi.org/10.1371/journal.pone.0245558

査読なし

2020年

47. Ji X, Ishikawa A, Nagata A, Yamada S, Imai H, Matsuda T, Takakuwa T, Relationship between rectal abdominis muscle position and physiological umbilical herniation and return: a morphological and morphometric study. Anat Rec (Hoboken) 2020, 303, 12, 3044-3051. doi: 10.1002/ar.24358

46. Nishitani S, Torii N, Imai H, Haraguchi R, Yamada S, Takakuwa T, Development of helical myofiber tracts in the human fetal heart: Analysis of myocardial fiber formation in the left ventricle from the late human embryonic period using diffusion tensor magnetic resonance imaging. Journal of the American Heart Association, 2020, 19(9), e016422, doi:10.1161/JAHA.120.016422

45. Tanaka S, Sakamoto R, Kanahashi T, Yamada S, Imai H, Yoneyama A, Takakuwa T. Shoulder girdle formation and positioning during embryonic and early fetal human development. PLoS One 2020, 15(9): e0238225. https://doi.org/10.1371/journal.pone.0238225

44. Fujii S, Muranaka T, Matsubayash J, Yamada S, Yoneyama A, Takakuwa T. The bronchial tree of the human embryo: an analysis of variations in the bronchial segments. J Anat 2020, 237, 311-322. doi: 10.1111/joa.13199.

43. Takakuwa T,Running course of the colon during the embryonic period, Clin Anat, 2020, 33, 628-9 (Letters to the editor) doi: 10.1002/ca.23469

⑬ Nakamura T, Yamada S, Funatomi T, Takakuwa T, Shinohara H, Sakai Y. Three-dimensional morphogenesis of the omental bursa from four recesses in staged human embryos. J Anat, 2020 ;237:166-175. doi: 10.1111/joa.13174.

42. Nagata A, Hatta S, Imai H, Yamada S, Takakuwa T. Position of the cecum in the extraembryonic and abdominal coelom in the early fetal period. Congenit Anom (Kyoto) 2020, 60 (3) 87-88. doi: 10.1111/cga.12348.

41. Ohga A, Sakamoto R, Yamada S, Takakuwa T, Vesicular swelling in the cervical region with lymph sac formation in human embryos. Congenit Anom (Kyoto) 2020, 60, 62-67: 10.1111/cga.12339.（表紙に採用されました。）

査読なし

■ 高桑徹也. Willis輪の形成とその異常；形成過程と個体差、異常について.　In 脳の発生とその異常Clinical Neuroscience (38巻12号, 1598-1601) 2020 中外医学社

■ 金橋　徹、高桑徹也；ヒト胚子期で起こる生理的臍帯ヘルニアと肝臓形態形成の関連性, Photon Factory Activity Report 2019 #37 (2020) [BL-14C/2019G542]

■ 金橋　徹、藤井瀬菜、高桑徹也；4消化器系（体腔と体壁の形成を含む）呼吸器系の発生 In 発生から紐解く　胎児超音波診断アトラス．産婦人科の実際 11月臨時増刊号、(69巻 12号1251-1260) 2020年、金原出版

■ 高桑徹也、金橋　徹；５泌尿器・生殖器系の発生 In 発生から紐解く　胎児超音波診断アトラス．産婦人科の実際 11月臨時増刊号、(69巻 12号1261-1268) 2020年、金原出版

2019年

40. Matsubayashi J, Okuno K, Fuji S, Ishizu K, Yamada S, Yoneyama A, Takakuwa T. Human embryonic ribs all progress through common morphological forms irrespective of their position on the axis, Dev Dyn 2019, 248, 1257-1263, doi: 10.1002/dvdy.107

39. Okuno K, Ishizu K, Matsubayashi J, Fujii S, Sakamoto R, Ishikawa A, Yamada S, Yoneyama A, Takakuwa T. Rib cage morphogenesis in the human embryo: A detailed three-dimensional analysis. Anat Rec (Hoboken) 2019, 302, 2211-2223, doi: 10.1002/ar.24226

38. Kanahashi T, Yamada S, Yoneyama A, Takakuwa T. Relationship Between Physiological Umbilical Herniation and Liver Morphogenesis During the Human Embryonic Period: A Morphological and Morphometric Study. Anat Rec (Hoboken) 2019, 302, 1968-1976. doi: 10.1002/ar.24149.

37. Ishiyama H, Ishikawa A, Imai H, Matsuda T, Yoneyama A, Yamada S, Takakuwa T. Spatial relationship between the metanephros and adjacent organs according to the Carnegie stage of development. Anat Rec (Hoboken) 2019. 302, 1887-2104. DOI: 10.1002/ar.24103

⑫ Katsube, M, Yamada, S, Yamaguchi Y, Takakuwa T, Yamamoto A, Imai H,Saito A, Shimizu A,Suzuki S. Critical Growth Processes for the Midfacial Morphogenesis in the Early Prenatal Period. Cleft Palate-Craniofacial J, 56, 1026–1037, 2019, https://doi.org/10.1177/1055665619827189

⑪ Saito A, Tsujikawa M, Takakuwa T, Yamada S, Shimizu A, Level set distribution model of nested structures using logarithmic transformation. Medical Image Analysis 2019, 56, 1-10. doi.org/10.1016/j.media.2019.05.003

⑩ Nakamura T, Shinohara H, Okada T, Hisamori S, Tsunoda S, Obama K, Kurahashi Y, Takai A, Shimokawa T, Matsuda S, Makishima H, Takakuwa T, Yamada S, Sakai Y. Revisiting the infracardiac bursa by multimodal methods. J Anat, 2019, 235, 88-95 doi: 10.1111/joa.12989

36. Suzuki Y, Matsubayashi J, Ji X, Yamada S, Yoneyama A, Imai H, Matsuda T, Aoyama T, Takakuwa T Morphogenesis of the femur at different stages of normal human development, PLoS One, 14(8): e0221569. https://doi.org/10.1371/journal. pone.0221569

35. Nagata A, Hatta S, Ji X, Ishikawa A, Sakamoto R, Yamada S, Imai H, Matsuda T, Takakuwa T. Return of the intestinal loop to the abdominal coelom after physiological umbilical herniation in the early fetal period. J Anat, 2019, 234, 456-464.doi: 10.1111/joa.12940.

査読なし

■ Takakuwa T, Matsubayashi J, Analysis of Central Nervous System and Skeletal System During Human Early-fetal Period Based on Multidisciplinary Computational Anatomy- Progress Overview FY2018 -, Proceedings of The 4th  International Symposium on Multidisciplinary Computational Anatomy, 2019

■ 原口 亮，西谷 早織，今井 宏3，高桑 徹也; ヒト胎児心臓心尖部における渦状線維走向の画像解析手法の検討; Proceedings of the 63rd Annual Conference of the Institute of Systems, Control and Information Engineers (ISCIE), Osaka, 2019 

2018年

34. Ishiyama H, Ishikawa A, Kitazawa H, Fujii S, Matsubayashi J, Yamada S, Takakuwa T, Branching morphogenesis of the urinary collecting system in the human embryonic metanephros, PLoS One 13(9): e0203623. doi: 10.1371/journal.pone.0203623

⑨ Kasahara K, Saito A, Takakuwa T, Yamada S, Matsuzoe H, Hontani H, Shimizu A. A spatiotemporal statistical shape model of the brain surface during human embryonic development. Advanced Biomedical Engineering 7, 2018, 146-155, DOI:10.14326/abe.7.146

■ Xiang Ji, Takakuwa T, Takahashi M, Iijima H, Morino S, Ishihara M, Kawagoe M, Hadanaka Y, Umezaki F, Yamashita M, Aoyama T, Postpartum radiographic changes in pelvic morphology and its relation with symptoms of pregnancy-related symphysis pain, Clin Exp Obst Gynecol, 2018, 45,665-670.DOI: 10.12891/ceog3964.2018

33.Furuichi K, Ishikawa A, Uwabe C, Makishima H, Yamada S, Takakuwa T. Variations of the circle of Willis at the end of the human embryonic period, 2018, Anat Rec (Hoboken) 2018, 301, 1312-1319, doi:10.1002/ar.23794　(Willis輪の形成とその異常)

⑧ Tojima S, Makishima H, Takakuwa T, Yamada S. Tail reduction process during human embryonic development. J Anat, 2018, 232,806-811, 10.1111/joa.12774

⑦ Miyazaki R, Makishima H, Männer J, Sydow HG, Uwabe C, Takakuwa T, Viebahn C, Yamada S. The Blechschmidt Collection: revisiting specimens from a historical collection of serially sectioned human embryos and fetuses using modern imaging techniques, Congenit Anom (Kyoto) 2018, 58, 152-157, doi: 10.1111/cga.12261 (ゲッティンゲン大学(独)との共同研究です。）

32. Ishikawa A, Ohtsuki S, Yamada S, Uwabe C, Imai H, Matsuda T, Takakuwa T. Formation of the periotic space during the early fetal period in humans, Anat Rec (Hoboken) 2018, 301(4);563-570, 10.1002/ar.23764, 10.1002/ar.23657,（概要）, 表紙に採用されました。

31. Ohtsuki S, Ishikawa A, Yamada S, Imai H, Matsuda T, Takakuwa T, Morphogenesis of the middle ear during fetal development as observed via magnetic resonance imaging. Anat Rec (Hoboken) 2018, 301, 757-764, doi: 10.1002/ar.23760（概要）

30. Takakuwa T, 3D analysis of human embryos and fetuses using digitized datasets from the Kyoto Collection, Anat Rec (Hoboken) 2018, 301,960-969 doi: 10.1002/ar.23784(総説）[2008年から開始したヒト胚子・胎児研究についてまとめました ]

査読なし

■ Takakuwa T, Okuno K, Yamada S, Analysis of Central Nervous System and Skeletal System During Human Early-fetal Period Based on Multidisciplinary Computational Anatomy- Progress Overview FY2017 -, Proceedings of The 3rd  International Symposium on Multidisciplinary Computational Anatomy, 2018, 151-155.

2017年

⑥ Katsube M, Yamada S, Miyazaki R, Yamaguchi Y, Makishima H, Takakuwa T, Yamamoto A, Fujii Y, Morimoto N, Ito T, Imai H, Suzuki S, Quantitation of nasal development in the early prenatal period using geometric morphometrics and MRI: A new insight into the critical period of Binder phenotype. Prenatal Diag 37: 907–915, 2017, DOI: 10.1002/pd.5106.2017 (表紙に採用されました）

29. Osaka M, Ishikawa A, Yamada S, Uwabe C, Imai H, Matsuda T, Yoneyama A, Takeda T, Takakuwa T, Positional changes of the ocular organs during craniofacial development, Anat Rec (Hoboken) 300(12), 2107–2114, 2017 DOI: 10.1002/ar.23588（概要）

27. Yoshida R, Ishizu K, Yamada S, Uwabe C, Okada T, Togashi K, Takakuwa T, The dynamics of gyrification in the human cerebral cortex during development, Congenit Anom (Kyoto) 57 (1) 8-14, 2017, DOI: 10.1111/cga.12179, 10.1111/cga.12181

査読なし

■ Takakuwa T, Muranaka T, Yamada S, Three-dimensional Analysis of the Bronchial Branching in Human Embryonic Stages- Progress Overview FY2016 -, Proceedings of The 2nd  International Symposium on Multidisciplinary Computational Anatomy, 2017, 45-48.

■ Takakuwa T. A novel strategy to reveal the latent liver abnormalities in human embryonic stages from a large embryo collection, PF Highlight 2016ハイライト記事.

■ 高桑徹也、尾脇なつみ；ヒト胚子期、胎児期初期における上気道、口腔の形態形成 (3D morphology and morphometry of the nasal and oropharynx region during the human embryonic and early fetal period), Photon Factory Activity Report 2016 #34(2017) [BL-14C/2015G574]

2016年

③ Sasaki K, Nakamura T, Okamoto I, Yabuta Y, Iwatani C, Tsuchiya H, Seita Y, Nakamura S, Shiraki N, Takakuwa T, Yamamoto T, Saitou M. The Germ Cell Fate of Cynomolgus Monkeys Is Specified in the Nascent Amnion. Develop cell, 2016 ;39 :169-185. DOI: doi: 10.1016/j.devcel.2016.09.007.

26. Ozeki-Satoh M, Ishikawa A, Yamada S, Uwabe C, Takakuwa T. Morphogenesis of the Middle Ear Ossicles and Spatial Relationships with the External and Inner Ears during the Embryonic Period, Anat Rec (Hoboken) 299:1325–1337, 2016, DOI 10.1002/ar.23457, (概要)

25. Takakuwa T, Koike T, Muranaka T, Yamada S, Uwabe C. 2016. Formation of the circle of Willis during human embryonic development. Congenit Anom (Kyoto) 2016; 56, 233–236, DOI: 10.1111/cga.12165

② Mehemed TM, Fushimi Y, Okada T, Kanagaki M, Okada T, Yamamoto A, Takakuwa T, Yamada S, Togashi K, Magnetic resonance imaging of pituitary gland and postsphenoid ossification in fetal specimens, Am J Neuroradiology 37 (8):1523-7, 2016, 10.3174/ajnr.A4808. [Open Access]

24. Hirose A, Nakashima T, Shiraki N, Yamada S, Uwabe C, Kose K, Takakuwa T, 3D models related to the publication: Morphogenesis of the liver during the human embryonic period, MorphoMuseuM 1(4) e1, 2016, doi: 10.18563/m3.1.4.e1

23. Kobayashi A, Ishizu K, Yamada S, Uwabe C, Kose K, Takakuwa T, Morphometric human embryonic brain features according to developmental stage, Prenatal Diagnosis, 36:338–345, 2016, DOI: 10.1002/pd.4818, DOI: 10.1002/pd.4786.

22. Ueno S, Yamada S, Uwabe C, Männer J, Shiraki N, Takakuwa T, The digestive tract and derived primordia differentiate by following a precise timeline in human embryos between Carnegie stages 11 and 13, Anat Rec (Hoboken) 2016,  299, 439-449, DOI: 10.1002/ar.23314s,  (概要)

21. Ozeki-Sato M, Yamada S, Uwabe C, Ishizu K, Takakuwa T, Correlation of external ear auricle formation with staging of human embryos, Congenit Anom (Kyoto) 56, 86-90, 2016, DOI: 10.1111/cga.12140,  (概要)

20. Nako A, Kaigai N, Shiraki N, Yamada S, Uwabe C, Kose K, Takakuwa T, 3D models related to the publication: Morphogenesis of the stomach during the human embryonic period, MorphoMuseuM, 1(4) e3,2016, doi: 10.18563/ m3.1.4.e3

① Kishimoto H, Yamada S, Kanahashi T, Yoneyama A, Imai H, Matsuda T, Takeda T, Kawai K, Three-dimensional observation of palatal muscles in the human embryo and fetus: development of levator veli palatini and clinical importance of the lesser palatine nerve, Developmental Dynamics 245: 123–131, 2016,  DOI: 10.1002/dvdy.24382, DOI: 10.1002/dvdy.24364

19. Ueda Y, Yamada S, Uwabe C, Kose K, Takakuwa T, Intestinal rotation and physiological umbilical herniation during the embryonic period, Anat Rec (Hoboken) 299, 197-206, 2016, DOI: 10.1002/ar.23296

18. Kanahashi T, Yamada S, Tanaka M, Hirose A, Uwabe C, Kose K, Yoneyama A, Takeda T, Takakuwa T, A novel strategy to reveal the latent abnormalities in human embryonic stages from a large embryo collection, Anat Rec (Hoboken) 299,8-24,2016  10.1002/ar.23281(概要), *299(1),2016の表紙に採用されました。DOI: 10.1002/ar.23206 (cover page)

査読なし

■ Takakuwa T, Muranaka T, Yamada S, Three-dimensional Analysis of the Bronchial Branching in Human Embryonic Stages- Progress Overview FY2015 -, Proceedings of The 2nd  International Symposium on Multidisciplinary Computational Anatomy, 2016, 43-46.

■ 高桑徹也、大坂美穂；ヒト器官形成期の視覚器の位置の移動について (The movement of Visual organs during cranio-facial development), Photon Factory Activity Report 2015 #33(2016)B [BL-14C/2015G574]

2015年

17. Toyoda S, Shiraki N, Yamada S, Uwabe C, Imai H, Matsuda T, Yoneyama A, Takeda T, Takakuwa T, Morphogenesis of the inner ear at different stages of normal human development.   Anat Rec (Hoboken) 298:2081–2090 (2015), doi: 10.1002/ar.23268　＊AR WOW Video article

16. Toyoda S, Shiraki N, Yamada S, Uwabe C, Imai H, Matsuda T, Yoneyama A, Takeda T, Takakuwa T, 3D models related to the publication: Morphogenesis of the inner ear at different stages of normal human development. MorphoMuseuM 1 (3)-e6. doi: 10.18563/m3.1.3.e6   ＊1巻3号の表紙に採用されました。

15. Shiraishi N, Katayama A, Nakashima T, Shiraki N, Yamada S, Uwabe C, Kose K, Takakuwa T, 3D model related to the publication: Morphology of the human embryonic brain and ventricles,  MorphoMuseuM 1 (3)-e3. doi: 10.18563/m3.1.3.e3. [OpenAccess]

14. Zhang X, Aoyama T, Takaishi R, Higuchi S, Yamada S, Kuroki H, Takakuwa T, Spatial change of cruciate ligaments in rat embryo knee joint by three-dimensional reconstruction.PLoS One. 2015 Jun 22;10(6):e0131092. doi: 10.1371/journal.pone.0131092. eCollection 2015., [OpenAccess]

13. Shiraishi N, Katayama A, Nakashima T, Yamada S, Uwabe C, Kose K, Takakuwa T, Morphology and morphometry of the human embryonic brain: A three-dimensional analysis, NeuroImage, 2015, 115, 96-103, 10.1016/j.neuroimage.2015.04.044, (概要), [OpenAccess]

12. Shiraishi N, Katayama A, Nakashima T, Yamada S, Uwabe C, Kose K, Takakuwa T, Three-dimensional morphology of the human embryonic brain, Data in Brief, 2015, 4, 116-118, 10.1016/j.dib.2015.05.001 [OpenAccess]

11. Endo A, Ueno S, Yamada S, Uwabe C, Takakuwa T, Morphogenesis of the spleen during the human embryonic period,  Anat Rec (Hoboken) 2015, 298, 820-826, doi: 10.1002/ar.23099（概要） [OpenAccess]

10. Taketani K, Yamada S, Uwabe C, Okada T, Togash K, Takakuwa T, Morphological features and length measurements of fetal lateral ventricles at 16–25 weeks of gestation by magnetic resonance imaging, Congenit Anom (Kyoto), 2015, 55, 99-102. doi: 10.1111/cga.12076（概要） [OpenAccess]

査読なし

■ Yamada S, Hill M, Takakuwa T, Chapter 5, Human Embryology, (Wu B, editor) New Discoveries in Embryology Open Access Publisher, Rijeka, Croatia, 2015, pp 97-124. ISBN 978-953-51-2182-4

■ 高桑徹也、豊田彩希、白木直人；ヒト胚子内耳形成の3次元的解析 (3D morphogenesis of inner ear of human embryo), Photon Factory Activity Report 2014  [BL-14C:2013G514]

■ 岸本 将志、斉藤 篤、大坂 美穂、高桑 徹也、山田 重人、清水 昭伸、ヒト胚子の眼球を対象とした時空間統計モデルに関する初期検討、信学技報, 2015

2014年 

9. Takaishi R, Aoyama T, Zhang X, Higuchi S, Yamada S, Takakuwa T; Three-dimensional reconstruction of rat knee joint using episcopic fluorescence image capture, Osteoarthritis Cartilage, 2014; 22(10), 1401-1409. 10.1016/j.joca.2014.06.016（概要）, [OpenAccess]  

 (Editorialで紹介されました), [OpenAccess]

 (297巻５号の表紙に採用, AR WOW video articleに選定されました) [OpenAccess]

査読なし

■ Takakuwa T and Kanahashi T, Two cases of liver agenesis detected in externally normal human embryos: A novel abnormality resulting in abortion during the embryonic period ( 外表正常ヒト胚子にみられた肝臓無形成の２例；流産に陥ると考えられる新たな異常例の報告), Photon Factory Activity Report 2013

2013年

7. Fujioka R, Aoyama T, Takakuwa T, The layered structure of the articular surface, Osteoarthritis Cartilage, 2013, 21, 1092-1098 doi: 10.1016/j.joca.2013.04.021（概要）, [OpenAccess]

6. Shiraishi N, Nakashima T, Yamada S, Uwabe C, Kose K, Takakuwa T, Morphogenesis of lateral choroid plexus during human embryonic period, Anat Rec (Hoboken). 2013 Apr;296(4):692-700. doi: 10.1002/ar.22662（概要）, [OpenAccess]

5. Hamabe Y, Hirose A, Yamada S, Uwabe C, Okada T, Togashi K, Kose K, Takakuwa T, Morphology and Morphometry of Fetal Liver at 16–26 Weeks of Gestation by Magnetic Resonance Imaging – Comparison with Embryonic Liver at Carnegie Stage 23, Hepatol Res,2013; 43: 639–647, doi: 10.1111/hepr.12000 （概要）

4. Shiraishi N, Yamada S, Takakuwa T. Three-dimensional Models Once Again – for research and teaching of early human development, Congenit Anom (Kyoto), 2013; 53(1), 58-59, doi: 10.1002/ar.22662 （概要）

査読なし

■ 高桑徹也、発生(第17章)、標準臨床検査学「基礎医学-人体の構造と機能」医学書院, P.332-340 (日本語総説）(外部紹介ページ）

2012年

3. Kagurasho M, Yamada S, Uwabe C, Kose K, Takakuwa T, Movement of the external ear in human embryo, Head Face Med. 2012 Feb 1;8(1):2, doi: 10.1186/1746-160X-8-2　（概要） 

2. Nakashima T, Hirose A, Yamada S, Uwabe C, Kose K, Takakuwa T, Morphometric analysis of the brain vesicles during the human embryonic period by magnetic resonance microscopic imaging, Congenit Anom (Kyoto). 2012 Mar;52(1):55-8, doi; 10.1111/j.1741-4520.2011.00345.x （概要), [OpenAccess]

1. Hirose A, Nakashima T, Yamada S, Uwabe C, Kose K, Takakuwa T, Embryonic liver morphology and morphometry by magnetic resonance microscopic imaging ,  Anat Rec (Hoboken). 2012 Jan;295(1):51-9., doi; 10.1002/ar.21496（概要) , [OpenAccess], (AR highlightsで紹介されました), [OpenAccess]

査読なし

■ Yamada S, Takakuwa T. (著書；editor)  the Human Embryo, InTech – Open Access Publisher, Rijeka, Croatia, 2012, 180P

–Yamada S, Takakuwa T, (執筆）Introduction: Overview of development in human embryos, P3-20.

–Yamada S, Nakashima T, Hirose A, Takakuwa T et al,（執筆）Developmental Anatomy of the Human Embryo: 3D-Imaging and Analytical Techniques, P111-126.

2011年

■ Pyothorax-associated lymphoma: Loss of Epstein-Barr virus nuclear antigen-3B protein expression as a result of mismatch repair phenotypes, 健康科学(人間健康科学系専攻、紀要),2011;7:17-22

■ Tsuruyama T, Maruyama Y, Kanaya K, Takakuwa T et al, MLV integration induces the formation of transcription factor complexes on palindromic sequences in the Stat5a gene during the development of pre-B lymphomagenesis, Am J Pathol. 2011;178(3):1374-86, doi; 10.1016/j.ajpath.2010.12.012

査読なし

■ 塩田浩平、山田重人、土屋真衣子、中島　崇、高桑徹也、他；マイクロイメージング法を用いたヒト胚子・胎児の骨格系と中枢神経系の観察ならびにその定量的解析.　小児の脳神経 2011; 36(1): 1-6 (精神・神経疾患研究開発費ー総括研究報告書)

アーカイブ

2010年

■ 　Tsuruyama T, Maruyama Y, Kanaya K, Takakuwa T et al. Dual retrovirus integration tagging: identification of new signaling molecules Fiz1 and Hipk2 that are involved in the IL-7 signaling pathway in B lylymphomas, J Leukoc Biol. 2010; 88(1):107-16.
■ 　Richard H. Kaszynski, Maruyama Y, Kanaya K, Takakuwa T et al, A quantitative trait locus responsible for inducing B‐cell lymphoblastic lymphoma is a hotspot for microsatellite instability, Cancer Sci, 2010; 101(3): 800-5

2009年

■ 　Oji Y, Takakuwa T, et al, WT1 IgG antibody for early detection of nonsmall cell lung cancer and as its prognostic factor. Int J Cancer. 2009;125(2):381-7. 2.
■ 　Takakuwa T, et al, Aberrant somatic hypermutations in thyroid lymphomas, Leukemia Research 2009 ;33(5):649-54.

2008年

■ 　Nur Rahadiani; Takakuwa T, et al, Latent membrane protein 1 of Epstein-Barr virus induces the expression of B-cell integration cluster, a precursor form of microRNA-155, in B lymphoma cell lines, BBRC, 2008;377(2):579-83.
■ 　Liu A, Takakuwa T, Fujita S, Luo WJ, Tresnasari K, van den Berg A, Poppema S, Aozasa K: ATRalterations in Hodgkin’s lymphoma. Oncology Report 19(4):999-1005, 2008.
■ 　Takakuwa T, Tresnasari K, Rahadiani N, Miwa H, Daibata M, Aozasa K, Cell origin of pyothorax-associated lymphoma; a lymphoma strongly associated with Epstein-Barr virus infection, Leukemia, 22(3):620-7, 2008.
■ 　Aozasa, K, Takakuwa T, Hongyo T, Yang W-I. Nasal NK/T-cell lymphoma: Epidemiology and pathogenesis. Int J Hematol ;87(2):110-7, 2008.
■ 　Inoue M, Takakuwa T, Minami M, Shiono H, Utsumi T, Kadota Y, Nasu T, Aozasa K, Okumura M, Clinicopathologic factors influencing postoperative prognosis in patients with small-sized adenocarcinoma of the lung, J Thorac Cardiovasc Surg;135(4):830-6, 2008

2007年

■ 　Tresnasari K, Takakuwa T, Ham MF, Rahadiani N, Nakajima H, Aozasa K.: Telomere dysfunction and inactivation of the p16(INK4a)/Rb pathway in pyothorax-associated lymphoma. Cancer Sci. 98(7):978-84, 2007.
■ 　Ham MF, Takakuwa T, Rahadiani N, Tresnasari K, Nakajima H, Aozasa K.: Condensin mutations and abnormal chromosomal structures in pyothorax-associated lymphoma. Cancer Sci.;98(7):1041-7, 2007.
■ 　Daibata M, Nemoto Y, Bandobashi K, Kotani N, Kuroda M, Tsuchiya M, Okuda H, Takakuwa T, Imai S, Shuin T, Taguchi H.: Promoter hypermethylation of the bone morphogenetic protein-6 gene in malignant lymphoma. Clin Cancer Res ;13:3528-35, 2007.

2006年

■ 　Hatano K, Ichimaru N, Takao T, Yoshimura K, Okuyama A, Takakuwa T, Aozasa K, Nakata Y, Okumoto Y, Hiraoka H. Paraganglioma of the urinary bladder: a case report. Hinyokika Kiyo. 52: 55-8, 2006.
■ 　Kurniawan AN, Hongyo T, Hardjolukito ESR, Ham MF, Takakuwa T, Kodariah R, Hoshida Y, Nomura T, Aozasa K: Gene mutation analysis of sinonasal lymphomas in Indonesia. Oncol Rep 15: 1257-63, 2006.
■ 　Takakuwa T, Ham MF, Luo WJ, Nakatsuka S, Daibata M, Aozasa K: Loss of expression of Epstein-Barr virus nuclear antigen-2 correlate with poor prognosis of pyothorax-associated lymphoma. Int J Cancer 52: 55-58, 2006.
■ 　Ishikawa SE, Nakatsuka S, Tomita Y, Fujita S, Nakamichi I, Takakuwa T, Sugiyama H, Fukuhara S, Hino M, Kanamaru A, Soma T, Tsukaguchi M, Igarashi K, Kanakura Y, Aozasa K, Osaka Lymphoma Study Group: Prognostic significance of BACH2 expression in diffuse large B- cell lymphoma. J Clin Oncol 23: 8012-7, 2006.
■ 　Ikeda JI, Morii E, Kimura H, Tomita Y, Takakuwa T, Hasegawa JI, Kim YK, Miyoshi Y, Noguchi S, Nishida T, Aozasa K: Epigenetic regulation of the expression of the novel stem cell marker CDCP1 in cancer cells. J Pathol 210: 75-84, 2006.
■ 　Liu A, Takakuwa T, Luo WJ, Fujita S, Aozasa K: Alterations in ATR in nasal NK/T-cell lymphoma and chronic active Epstein-Barr virus infection. Cancer Sci. 97:605-10, 2006
■ 　Ham MF, Takakuwa T, Luo WJ, Liu A, Horii A, Aozasa K: Impairment of double-strand breaks repair and aberrant splicing of ATM and MRE11 in leukemia-lymphoma cell lines with microsatellite instability. Cancer Sci. 97: 226-34, 2006.

2005年

■ 　Akimau P, Yoshia K, Hosotsubo H, Takakuwa T, Tanaka H, Sugimoto H: New experimental model of crush injury of hindlimbs in rats. J Trauma 58: 51-58, 2005.
■ 　Takakuwa T, Luo WJ, Ham MF, Wada N, Aozasa K: Identificatioan of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Research 108: 133-138, 2005.
■ 　Liu A, Takakuwa T, Fujita S, Ham MF, Luo WJ, Daibata M, Aozasa K: Alterations of DNA damage-response genes ATM and ATR in pyothorax-associated lymphoma. Lab Invest 85: 436-446, 2005.
■ 　Nakamichi I, Takakuwa T, Tanio Y, Iuchi K, Aozasa K. Pyothorax-associated lymphoma: an unusual case with both T- and B-cell genotypes. Virchows Arch: 447: 888-91, 2005
■ 　Aozasa K, Takakuwa T, Nakatsuka S: Pyothorax-associated lymphoma-a lymphoma developing in chronic inflammation. Adv Anat Pathol, 12: 324-31, 2005.

2004年

■ 　Nagasawa T, Takakuwa T, Takayama H, Dong Z, Miyagawa S, Itami S, Yoshikawa K, Aozasa K: Fas Gene Mutations in Mycosis fungoides: Analysis of Laser Capture-Microdissected Specimens from Cutaneous Lesions. Oncology 67: 130-134, 2004.
■ 　Nishiu M, Tomita Y, Nakatsuka S, Takakuwa T, Iizuka N, Hoshida Y, Ikeda J, Iuchi K, Yanagawa R, Nakamura Y, Aozasa K: Distinct pattern of gene expression in pyothorax-associated lymphoma (PAL), a lymphoma developing in long-standing inflammation. Cancer Sci 95: 828-834, 2004.
■ 　Takakuwa T, Luo WJ, Ham MF, Sakane-Ishikawa F, Wada N, Aozasa K: Integration of Epstein-Barr virus into chromosome 6q15 of Burkitt lymphoma cell line (Raji) induce loss of BACH2 expression. Am J Pathol 164: 967-974, 2004. (医学博士論文)
■ 　Luo WJ, Takakuwa T, Ham MF, Wada N, Liu A, Fujita S, Sakane-Ishikawa E, Aozasa K: Epstein-Barr virus is integrated between REL and BCL-11A in American Burkitt lymphoma cell line (NAB-2). Lab Invest 84: 1193-1199, 2004.
■ 　Miyazato H, Nakatsuka S, Dong Z, Takakuwa T, Oka K, Hanamoto H, Tatsumi Y, Kanamaru A, Aozasa K; Osaka Lymphoma Study Group: NK-cell related neoplasms in Osaka, Japan. Am J Hematol 76: 230-235, 2004.
■ 　Takakuwa T, Luo WJ, Ham MF, Aozasa K: A 50-bp Insertion from Intron 2 Between Exons 2 and 3 of NBS1 May be a Spliced Variant. Genes Chrom Cancer 39: 341-342, 2004.
■ 　Tsujimoto Y, Takakuwa T, Takayama H, Nishimura K, Okuyama A, Aozasa K, Nonomura N: In situ shortening of CAG repeat length within the androgen receptor gene in prostatic cancer and its possible precursors. Prostate 58: 283-290, 2004.

2003年

■ 　Takakuwa T, Luo WJ, Ham MF, Mizuki M, Iuchi K, Aozasa K: Establishment and characterization of unique cell lines derived from pyothorax-associated lymphoma which develops in long-standing pyothorax and strongly associated Epstein-Barr virus infection. Cancer Sci 94: 858-863, 2003.
■ 　Nakatsuka S, Liu A, Yao M, Takakuwa T, Tomita Y, Hoshida Y, Nishiu M, Aozasa K: Methylation of promoter region in p27 gene plays a role in the development of lymphoid malignancies. Int J Oncol 22: 561-568, 2003.
■ 　Nakatsuka S, Liu A, Dong Z, Nomura S, Takakuwa T, Miyazato H, Aozasa K; Osaka Lymphoma Study Group: Simian virus 40 sequences in malignant lymphomas in Japan. Cancer Res 63: 7606-7608, 2003.
■ 　Nakatsuka S, Takakuwa T, Tomita Y, Hoshida Y, Nishiu M, Yamaguchi M, Nishii K, Yang WI, Aozasa K: ■ 　Hypermethylation of death-associated protein (DAP) kinase CpG island is frequent not only in B-cell but also in T- and natural killer (NK)/T-cell malignancies. Cancer Sci 94: 87-91, 2003.
■ 　青笹克之　星田義彦　高桑徹也: リンパ腫の発症機序２）ウイルス. 押味和夫(編) 悪性リンパ腫の基礎と臨床, 医薬ジャーナル社, pp45-52, 2003.

2002年

■ 　Takayama H, Takakuwa T, Tsujimoto Y, Tani Y, Nonomura N, Okuyama A, Nagata S, Aozasa K: Frequent mutations of FAS gene in testicular germ cell tumors. Am J Pathol 161: 635-641, 2002.
■ 　Takakuwa T, Dong Z, Nakatsuka S, Kojya S, Harabuchi Y, Yang WI, Nagata S, Aozasa K: Frequent mutations of Fas gene in nasal NK/T cell lymphoma. Oncogene 21: 4702-4705, 2002.
■ 　Dong Z, Takakuwa T, Takayama H, Luo WJ, Takano T, Amino N, Matsuzuka F, Aozasa K: Fas and Fas ligand gene mutations in Hashimoto’s Thyroiditis. Lab Invest 82: 1611-1616, 2002.
■ 　Hoshida Y, Hongyo T, Nakatsuka S, Nishiu M, Takakuwa T, Tomita Y, Nomura T, Aozasa K: Gene mutations in lymphoproliferative disorders of T and NK/T cell phenotypes developing in renal transplant patients. Lab Invest 82: 257-264, 2002.
■ 　Takayama H, Takakuwa T, Tsujimoto Y, Nonomura N, Okuyama A, Aozasa K: Analysisi of Fas gene mutations on laser capture microdissected specimens from renal cell carcinoma. Jpn J Cancer Res 93: 1201-1206, 2002
■ 　Miwa H, Takakuwa T, Nakatsuka S, Tomita Y, Iuchi K, Aozasa K: DNA sequence of immunoglobulin heavy chain variable region gene in pyothorax-associated lymphoma. Oncology 62: 241-250, 2002.
■ 　Yamauchi A, Tomita Y, Takakuwa T, Hoshida Y, Nakatsuka S, Sakamoto H, Aozasa K: PCR-based clonality analysis in thyroid lymphoma. Int J Molecular Medicine 10: 113-117, 2002
■ 　Nakatsuka S, Nishiu M, Tomita Y, Miwa H, Takakuwa T, Iuchi K, Yamamoto S, Aozasa K: Enhanced Expression of Neuron-specific Enolase (NSE) in Pyothorax-associated Lymphoma (PAL). Jpn J Cancer Res 93: 411-416, 2002.
■ 　鎌野寛、岡田泰士、山神真一、窪田良次、田中輝昭、高桑徹也: 運動の強度がヒトの免疫能に及ぼす効果について. 地域環境保健福祉研究 6: 1-6, 2002.
■ 　高桑徹也、遠藤重厚: スキーとスノーボードによる骨盤部外傷とその治療.整災外 45, 1255-1262, 2002

2001年

■ 　Nishimura R, Takakuwa T, Hoshida Y, Tsujimoto M, Aozasa K: Primary pancreatic lymphoma: clinicopathological analysis of 19 cases from Japan and review of the literature. Oncology 60: 322-329, 2001
■ 　Takakuwa T, Dong Z, Takayama H, Matsuzuka F, Nagata S, Aozasa K: Frequent mutations of Fas gene in thyroid lymphoma. Cancer Res 61: 1382-1385, 2001.
■ 　Takayama H, Takakuwa T, Dong Z, Nonomura N, Okuyama A, Nagata S, Aozasa K: Fas gene mutations in prostatic intraepithelial neoplasia and concurrent carcinoma: analysis of laser capture microdissected specimens. Lab Invest 81: 283-288, 2001.
■ 　Miwa H, Takakuwa T, Nakatsuka S, Tomita Y, Matsuzuka F, Aozasa K: DNA sequence of immunoglobulin heavy chain variable region gene in thyroid lymphoma. Jpn J Cancer Res 92: 1041-1047, 2001.
■ 　遠藤重厚、高桑徹也: スキー・スノーボード外傷とその治療と看護. Emerg Nursing 14: 26- 31, 2001
■ 　中塚伸一、高桑徹也、青笹克之: 悪性リンパ腫におけるDAP-kinase遺伝子のメチル化. 臨病理 49: 1242-1247, 2001.
■ 　青笹克之、高桑徹也、中塚伸一: 慢性炎症を基盤に発生する悪性リンパ腫. 日内科会誌 90: 75-79, 2001.
■ 　青笹克之、中塚伸一、高桑徹也: 慢性膿胸と悪性リンパ腫. Biotherapy 16: 153-160

2000年

■ 　Takakuwa T, Endo S, Shirakura Y, Yokoyama M, Tamatani M, Tohyama M, Aozasa K, Inada K: Interleukin-10 Gene Transfer Improves the Survival Rate of Mice Inoculated with E. coli. Critical Care Medicine 28: 2685-2689, 2000.
■ 　Takakuwa T, Nomura S, Matsuzuka F, Inoue H, Aozasa K: Expression of interleukin 7 and its receptor in thyroid lymphoma. Lab Invest 80: 1483-1490, 2000.
■ 　Takakuwa T, Hongyo T, Syaifudin M, Kanno H, Matsuzuka F, Narabayashi I, Nomura T, Aozasa K: Microsatellite instability and k-ras, p53 mutations in thyroid lymphoma. Jpn J Cancer Res 91: 280-286, 2000.
■ 　Nakatsuka S, Takakuwa T, Tomita Y, Miwa H, Matsuzuka F, Aozasa K: Role of hypermethylation of DAP-kinase CpG island in the development of thyroid lymphoma. Lab Invest 80: 1651-1655, 2000.